Dennis J. Thiele, Ph.D.
Chief Scientific Officer
Formerly Professor at Duke University and University of Michigan
Thought leader in the field of Heat Shock Transcription Factors
30+ years investigating structure, function, regulation and pharmacology of HSF1 in human cells, animal models and fungi
Jiaoti Huang, MD., Ph.D.
Chief Scientific Officer
Prof.& Chair, Depart. of Pathology, Duke Univ. School of Med.
Drove development of HSF1 inhibitor in Prostate Cancer
25+ years translational research on advanced Prostate Cancer
Sean E. O’Brien, Ph.D.
Chief Executive Officer
Small molecule discovery and startup expertise, Senhwa, Trilogy, Cylene
Directed multiple programs from preclinical to Clinical POC
20+ years in oncology R&D and corporate strategy
